Abstract:
The purpose of this study was to determine the effects of propofolxylazine
and propofol-xylazine-diazepam protocols on clinical and
haematological parameters in an attempts to produce safe and satisfactory
total intravenous anaesthesia in camel.
In this study two protocols were used:
Propofol-Xylazine protocol and Propofol-Xylazine-diazepam
protocol,camellus dromedaries was used as the experimental animal.
1-Propofol(1%) 2mg/kg+Xylazine(2%) 0.25mg/kg intraveinous injection
2- Propofol(1%) 2mg/kg+Xylazine(2%) 0.25mg/kg+Diazepam(0.5%)
0.25mg/kg as intraveinous injection
All anaesthetic protocols produced satisfactory induction and rapid smooth
recovery and there were significant increase in the duration of anaesthesia
phase(unconsciousness) during protocol two compared to protocol one
which may be attributed to the use of diazepam in protocol two. Significant
increase was also noticed in protocol two, in the duration of lateral
recumbency, sternal recumbency, standing position and total recovery time
was monitoring during course of anaethesia. Induction of anaesthesia,
muscle relaxation and recoveries were satisfactory in both protocols used.
The clinical and haematological parameters were measured before,during
and after anaesthesia at interval of 15,30,60,120 minutes throughout the
duration of the experiment.
VIII
The respiratory rate was anon significantly increase or decrease in both
propofol-xylazine and propofol-xylazine-diazepam protocols while the heart
rate was significantly decrease(p≤0.05) values of 51.8±5.4 compared to
base line values (59.6±1.7) from 30min post injection to 60min post
injection time during both regimes.Rectal temperature revealed no
significant changes in the two protocols used.
The red blood cells(R.B.Cs) and packed cell volume(PCV%) there was
significant decrease in protocol one and significant increase in protocol two
while haemoglobine concentration and white blood cells(W.B.Cs) there
were no changes except at 30min there significant increasein both protocols.
The study revealed that the mean of (mean±SD) of reflex , the
corneal reflex, spinal reflex,pedal reflex,anal reflex,tail reflex,lips
dropping,tongue protrusion and salivation was noted as follows:
(22.9)،(40.3)،(20.9)،(22.6)،(31)،(43.7)،(37)،(21.5) immediatelly.
On conclusion these protocols were proved to be safe for use as a
satisfactory anaesthetic in camel(camelus dromedaries).
