Abstract:
This is a descriptive analytical study carried out in Algleea
village near Shendi town ,in the period from (march 2012 ــJuly
2012) to evaluation some coagulation tests among Sudanese
Schistosomiasis patients in Algleea village 50 patients were
selected ,42(75%) male and 8(25%)female and 50 healthy
individuals were selected as a control group .Four and half ml of
venous blood were withdrawn from each patient; placed in tri
sodium citrate container , platelets were counts ,then we
centrifuge to separate platelets poor plasma (ppp) then we
assessed PT, APTT ,and D.dimer . The data analyzed by Statistical
Package for Social Sciences (SPSS) version 11.5, and express as
means. The results obtained from patients show that the mean
value of PT (prothrombin time), APTT (activated partial
thromboplastin time) D.dimer and platelets counts they use as
follows in patients group were (16sec) ,(34 sec), (342mg/dl),
(231cell) respectively . the, mean of PT, APTT, D.dimer and
platelets
counts
in
control
group,(13sec),(32sec),
(286mg/dl),153cell)respectively. The results showed no significant
difference between the mean of the patients and controls in the
prothrombin time (PT)(P.value>0.05) while result demonstrated a
significant differences between the mean of the patients and
control in activated partial thromboplastin time (APTT),D.dimer
and platelets counts insignfcant in both sex (P.value<0.05). The
result obtained indicated that measurement of prothrombin time
(PT) was unnecessary when evaluating Schistosomiasis patients
whom there were clinical evidence of haemostatic abnormality
.the results of this study raised the possibility of that an activated
partial thromboplastin time (APTT),D.dimer could be used in
identifying risk group of Schistosomiasis patients were likely to
develop thrombotic events, platelets counts unnecessary .