Evaluation of some haemostatic parameter Among Schistosomiasis parameters in Algleea village – Shendi

Abstract

This is a descriptive analytical study carried out in Algleea village near Shendi town ,in the period from (march 2012 ‫ ــ‬July 2012) to evaluation some coagulation tests among Sudanese Schistosomiasis patients in Algleea village 50 patients were selected ,42(75%) male and 8(25%)female and 50 healthy individuals were selected as a control group .Four and half ml of venous blood were withdrawn from each patient; placed in tri sodium citrate container , platelets were counts ,then we centrifuge to separate platelets poor plasma (ppp) then we assessed PT, APTT ,and D.dimer . The data analyzed by Statistical Package for Social Sciences (SPSS) version 11.5, and express as means. The results obtained from patients show that the mean value of PT (prothrombin time), APTT (activated partial thromboplastin time) D.dimer and platelets counts they use as follows in patients group were (16sec) ,(34 sec), (342mg/dl), (231cell) respectively . the, mean of PT, APTT, D.dimer and platelets counts in control group,(13sec),(32sec), (286mg/dl),153cell)respectively. The results showed no significant difference between the mean of the patients and controls in the prothrombin time (PT)(P.value>0.05) while result demonstrated a significant differences between the mean of the patients and control in activated partial thromboplastin time (APTT),D.dimer and platelets counts insignfcant in both sex (P.value<0.05). The result obtained indicated that measurement of prothrombin time (PT) was unnecessary when evaluating Schistosomiasis patients whom there were clinical evidence of haemostatic abnormality .the results of this study raised the possibility of that an activated partial thromboplastin time (APTT),D.dimer could be used in identifying risk group of Schistosomiasis patients were likely to develop thrombotic events, platelets counts unnecessary .