Abstract:
Streptococcus
pneumoniae is the most common cause of pneumonia
worldwide, and pneumonia is the most common manifestation of pneumococcal
infection.
This study was carried out in the research laboratory, college of medical
laboratory, Sudan University of science and technology in the period from April
to July 2012.
The aim of the study was to determine the frequency and susceptibility pattern
of S. pneumoniae among patients with lower respiratory tract infection in
Alshaab Teaching Hospital.
One hundred sputum specimens were collected from patients with lower
respiratory tract infections in Alshaab hospital. Ziehl Nelseen stain was done for
all specimens. Then all ZN stain negative smears were cultured on blood,
chocolate and MacConkey agars for isolation of S. pneumoniae. Identification
of isolates were done by colonial morphology, Gram stain, and biochemical
tests. And antibiotic sensitivity was performed to S. pneumoniae by disc
diffusion methods.
The result revealed that, 12% were S. pneumoniae, 8% were Escherichia coli,
5% were Pseudomonas aeruginosa, 21% were K. pneumoniae, 10% were S.
aureus , 2% were protus species and 23% were viridans streptococci.
and Showed that the S. pneumoniae was sensitive to chloramphnicol (100%),
ciprofloxacin (100%), tetracycline (75%), erythromycin (50%), and
was
resistance to penicillin (100%).
This study conduded that presence of S. pneumoniae isolates among patients
with LRTI in Khartoum State was 12%.
