Abstract:
This study conducted during the period of February to
July 2014, and aimed to compare between endpoint and
kinetic Jaffe’s method which are commonly used for
measurement of creatinine in practice in Sudan.
This study includes 40 samples collected from 40
volunteers (healthy) were selected randomly from the
western and southern sections of Sudan University of
Science and Technology.
All samples collected in heparin containers and the
plasma was separated. Aliquot of plasma was utilized in
duplicate to estimate the plasma creatinine level by
endpoint method and kinetic method.
All results were analyzed using SPSS program.
This study showed that there was statistical significant
difference between creatinine results obtained by using
endpoint method (mean = 1.1±.11 mg/dl) and kinetic
method (mean = .72±.27 mg/dl) with P.Value = 0.00
This study also reveals that there was statistically
significantly increases in creatinine level in males (n=30)
(mean=1.1±.11mg/dl) when compared with that of
females (n=10) (mean=1±.11) with P.Value =0.04 in
endpoint method.
This study also shows that there was statistically non
significantly increases in creatinine level in males
(mean=0.74±0.28mg/dl) (n=30) when compared with
that of females (n=10) (mean=0.67±0.22mg/dl) with
P.Value=0.48 in kinetic method.
From the results of this study, we conclude that There was
significant different between the result obtained by kinetic
and endpoint methods for creatinine estimation in the
plasma.
