Abstract:
This study was conducted during May 2001- March 2002 to evaluate the
lipid profile level (Total cholesterol, Triglycerides, LDL low density lipoprotein
cholesterol , HDL high density lipoprotein cholesterol ) in the blood plasma and
plasma albumin . of children with nephrotic syndrome .
Forty children (<15 years) affected by nephrotic syndrome were selected
from four different hospitals in Khartoum state (Soba hospital, Khartoum
Children Hospital , Ahmed Gasim Children Hospital and Omdurman Children
Hospital) and were compared with 20 healthy children as control group .( The
level of plasma lipids, lipoprotein and albumin were measured by colorimetric
method).
The mean plasma total cholesterol , ( cholesterol , trglycerides LDL iow
density lipoprotein cholesterol , HDL high density lipoprotein cholesterol) were
(269 + 50) , (170 +58) , 179 + 47) and ( 58 + 20 ) mg /dl, respectively in the
patients group compared to the mean (108 + 15) , (56 + 19) , (37 + 17 ) ,
(40 +13) mg /dl in the control group(P<0.0001)
This study indicate downward (─ve) the correlation between plasma
albumin level and plasma lipids level (total cholesterol , triglycerides , LDL low
density lipoprotein cholesterol, HDL high density lipoprotein cholesterol ) in
patients group .
