Abstract:
The kidney function was monitored in 70 hypertensive
Sudanese patients from Khartoum state in order to assess the
impact of hypertension in function of kidney in those patients.
Other 30 none hypertensive individuals were also participated
in this study to serve as control. Patients and controls were
matched in age and sex in which the average age of patients
was 52 years.
Five ml of blood are taken left to clot, then centrifuged to
obtain serum which used for estimation of Electrolytes Na+ &
K+ by flamephotometer, while Creatinine by Jaffe reaction and
Albumin by bromocresol green method by means of colorimeter
and
clear
urine
analyzed
for
protein
excretion
by
sulphosalycylic acid method.
The findings obtained from this study revealed that the
majority of the hypertensive patients are elderly, over 52 years
and most of them presented with many clinical complications of
cardiovascular diseases and coronary events. The study also
showed that family history of hypertension was present among
close relative of the study group.
Measuring electrolytes Na+ & K+
in the serum of
the
hypertensive patients of this study showed highly significant
increase level of Na+ compared to control (P<0.05), while K+
level showed no statistical difference between patients and
controls values (P>0.05). On the other hand Creatinine and
Albumin showed highly significant elevation in patients over
that
suggest
may
result
This
.)50.0>(P
values
control
hypertensive patients participated in this study at high risk to
.develop kidney disease and its complications
A result which may suggests that hypertension is an individual
.risk factor leading to kidney disease
