Abstract:
The study was carried out in Khartoum and Omdurman
teaching hospitals to determine the effect of Giardia lamblia on
hemoglobin level and total white blood cells. The study start in
May 2007 to end July 2007, one hundred and half stool samples
were collected and divided into three groups according to the
questionnaire and microscopic examination of stool to non
infected, infected before, and infected groups. Stool samples
wee examined by wet preparation and concentration techniques;
subsequently 150 blood samples were collected and analyzed
using colorimetric method for haemoglobin level. The total
white blood cells counts was done by using neubauer chamber.
Differential leukocytes counts was used leishman stain to stain
thin blood film.
In Giardia Lamblia the haemoglobin level was found to be
12.07 g\dl, 11.90 g\dl and 11.30 g\dl in non infected, infected
before and infected groups respectively. The haemoglobin level
decreased in infected group with Giardia Lamblia and show
significant differences between non infected and infected group
at P<0.05. Haemoglobin were found to be higher in males than
those of females in all groups. The level of haemoglobin in
males was found to be 12.9 g\dl, 12.3 g\dl and 11.6 g\dl in non
infected, infected before and infected groups respectively.
Whereas the level in females was found to be 11.30 g\dl, 11.6
g\dl and 10.9 g\dl non infected, infected before infected groups
respectively.
Mean of total leukocyte counts was found to be
4800c\cumm³, 5300 c\cumm³and 6190 c\cumm³ in non infected,
infected before and infected groups respectively. These results
showed that Giardia Lamblia infected group had higher
leukocyte count which exceed the mean of normal value. There
was very highly significant differences at p<0.01 level between
the non infected and infected group.
The mean of neutrophils count was found to be 58.86%,
57.88% and 65.02% in non infected, infected before and infected groups respectively. There was very highly significant
difference P<0.01 between the non infected and infected groups.
Giardia lamblia had lower lymphocytes count 27.06% in
infected group than 35.48% in infected before and 34.98%in
non infected groups. The means showed that very highly
significant difference P<0.01 between the non infected and
infected groups.
Infected group with Giardia lamblia had higher monocytes
cells count7.54% than those of infected before 4.76% and non
infected group 4.80%. The means were very highly significant
difference P<0.01 between the non infected and infected groups.
Eosinophils had higher cells count 2.3% of individuals who
were infected with G.Lamblia, than those of Infected before
0.43% and non infected group 0.20%, with very highly
significant differences p<0.01 between infected and infected
before groups.
Finally the means of Basophils cell counts were found to be
higher in individuals who were infected with G.Lamblia 0.40%
than those who had previous infection 0.24%, and 0.10% in
those who had no infection. There was significant different
p<0.05 between the infected and infected before groups.