Abstract:
Background: Combined oral contraceptives pills are the most popular
contraceptive method world-wide.50-60 % of women of reproductive age worldwide
use this method for birth control. Dyslipidemia occurs in long tern oral
contraceptives user women.
Objective: This study was aimed to evaluate lipid profile among women using
combined oral contraceptive pills in Gazira state.
Materials and methods: This was cross sectional study concluded sample were
collected using questionnaire the study conducted in Gazira state Total number
of 40 women which using oral contraceptive conducted as case group and 40 of
them not using oral contraceptive as control group ¸ fasting blood sample were
collected for the estimation of lipid profile (cholesterol¸ triglycride ¸HDL¸LDL)the
sample prepaired and spectrophotometrically measured ·
Result: analyzed result by using SPSS computer program version 22.0 with T test
and P value was obtained (P value ≤ 0.05 was considered statistically significant.
the mean of age in combined oral contraceptive group was (26.97± 6.21), the mean
of height in combined oral contraceptive group was (160.2 ± 7.99), the mean of
weight among case group was (88.8 ± 9.9) and mean of BMI was (34.3 ±3.32)
among case group while (27.3 ± 8.1) among control group(P.value was (0.003
)considered significant different,the mean of serum total cholesterol in combined
oral contraceptive group was (224.2 ± 26.7 mg/dL) and (183.0 ± 19.2 mg/dL)
among control group .P.value was (0.028 ) considered significant different ,the
mean of serum triglyceride in combined oral contraceptive group was (141.0± 20.0
mg/dL) and (95.3 ± 15.1 mg/dl ) among control (P.value was (0.001 )considered
significant different ,the mean of serum HDL-C in combined oral contraceptive
group was (43.3± 10.4mg/dL) and (56.5 ± 8.5mg/dl ) among control group(P.value
was (0.004 )considered significant different and the mean of serum LDL-C in
combined oral contraceptive group was (87.6±20.9 mg/dL) and (66.5±6.2mg/dl )
among control group(P.value was (0.001 )considered significant different .Most of
percentage presented that age group 20- 30 years among case population and
control as , Majority of them used contraceptive during 3 years, Majority of them
had used Familia contraceptive then few used Marvelon.
Conclusion: The study result concluded that women had received oral
contraceptive had higher level of total plasma cholesterol, triglyceride, LDL-C
while low level of HDL-C and insignificantly correlation between plasma total
cholesterol and (age, body mass index, and duration of combined oral
contraceptive use).
