Abstract:
Hypertensive pregnancy may be responsible for vascular
damage, enhanced systemic inflammation and insulin resistance in the
placenta as oxygen and nutrient transfer is impaired and oxidative stress
is generated affecting the placental growth and development.
Present study was done to investigate the changes in placenta
in hypertensive pregnancy. A total of 40 pregnant women with
hypertensive disorder were enrolled as cases in the study. A total of 40
matched normotensive pregnant women were enrolled as controls. All the
women were followed up and findings were compared with
normotensives. Data was compared using Independent sample t-test.
The results of the study showed the mean age of cases was
27.85 ± 6.09 years. Mean placental thickness in hypertensive pregnancy
was also higher (4.1±1.07) compared with normotensive (3.7 ± 0.7) but
difference was not significant statistically. Fetal Weight in Hypertensive
Pregnancy was (2 ± 0.94) compared to normotensive (2.5 ± 0.7), there is
a statistically significant difference. Hypertensive pregnancy does not
affect the location of the placenta.
Hypertension during pregnancy affects the placental growth and development.
