Abstract:
This study consists of 51 hyperthyroid patients of different ages, gander, weight
and heights whom were under different doses of medication (Carbimazole) and
were referred to nuclear medicine department for thyroid scan to follow-up their
response to medication by identifying the uptake of thyroid gland.
These patients were divided into three groups (A, B and C) depending on their
Thyroid Hormone Test (TFT) results while using medication. Each group been
stopped from their medication for a specific period (3, 5 and 7days), to check
whether patient’s thyroid hormone levels might elevate into a toxic level, and
whether the accuracy of thyroid images would increase by increasing the delay
period.
To measure the thyroid hormone levels, (TFT) been made for patients. Two
blood samples had been taken from each patient, the first while they were still
under medication, and the second was according to their group (A, B and C)
which is after 3, 5 and 7 days respectively.
To check the accuracy of thyroid images, the patients underwent thyroid scan
after a delay period of 3, 5 and 7 days respectively from medication. Images of
thyroid uptake of the three groups were compared after the acquisition of thyroid
scan has been made.
The study been conducted at Khartoum Oncology Hospital in Sudan, between
(Dec2018-Dec2019). The results showed that an elevation of thyroid hormones
occurs as the patient stops the medication, and it increases as the delay time
increases. In addition, it showed no significant increasing in the accuracy of
thyroid scan as the delay time increased, TFT was quite enough for determining
patient’s response to medication.
