Abstract:
This is a descriptive hospital base study conducted in
Khartoum state, during the period from December 2009 to
June 2010. This study aimed to identify the frequency of
Candida species in the oral cavity of diabetic patients in
Khartoum state. The samples were collected from 550
individuals divided
as follows: 500 specimens were
collected from diabetic patients as case group, their ages
ranged between 11 to 85 years. Other 50 specimens were
collected from non diabetic individuals as a control group.
Buccal smears were prepared fixed and stained using
Papanicolaou stain and examined under light microscope.
The cytological assessment among study group revealed
the following findings: 9.4% bacterial infection, 7.4% oral
candidiasis, 0.6% viral infection, 10.2% non specific
inflammatory
changes
and
0.4%
keratinization,
with
significant relation between cytological changes and
diabetes mellitus (p .value < 0.05), these changes depend
on the type and duration of diabetes mellitus and age of
patients.
The study found a significant relation between diabetes
mellitus and oral candidiasis (p value < 0.05) and these
relations depend on the type and duration of
Diabetes
mellitus.
This study concluded that oral candidiasis associated with
diabetes mellitus and causing cytological changes in the
oral cavity of diabetic patients; these changes depend on
the type and duration of Diabetes mellitus .
