Abstract:
A cross-sectional study conducted during the period from September
2009 to May 2010, compared plasma levels of total cholesterol, triglycerides,
HDL-cholesterol and LDL-cholesterol of 40 patients with diabetes mellitus type2
associated with ischemic heart disease as a study group and 30 patients with
diabetes type2 without ischemic heart disease as a control group. The study group
was chosen from diabetic patients admitted to the intensive care unit (ICU) of
Alshaap and Omdurman Teaching Hospitals for at least 5 days, and the control
group was selected from diabetic patients on regular follow up in the above
mentioned hospitals.
The plasma levels of total cholesterol, triglycerides, LDL-cholesterol
and HDL-cholesterol showed no significant difference (p>0.05) when the study
group was compared to the control group.
In patient with diabetes mellitus type2 associated with ischemic heart
disease the plasma levels of total cholesterol, triglycerides, LDL-cholesterol were
positively correlated with the duration of diabetes mellitus whereas there is no
correlation between the plasma of the HDL-cholesterol and the duration of the
disease.
From this study, it concluded that, in Sudanese patients with ischemic
heart disease due to diabetes mellitus type2 and on glycemic control their plasma
lipid profile is not significantly affected. The duration of diabetes mellitus type2
has positive correlation with the plasma levels of total cholesterol, triglycerides
and plasma levels of LDL-cholesterol but has no correlation with the plasma levels
of HDL-cholesterol.
