Abstract:
A cross-sectional study, conducted during the period
from October to December 2010, compared the plasma
levels of calcium, phosphate and glycated haemoglobin of
60 Sudanese patients suffering from type 2 diabetes
mellitus. A total of60 diabetic patients as a test group (30
males & 30 females) in addition to 60 apparently healthy
volunteers as a control group (30 males&30 females).
All the participants in this study were from Khartoum
state. The test groups (males &females) and the control
groups (males &females) were matched for age and sex.
The levels of the plasma calcium, phosphate were
determined in heparinized blood samples and glycated
hemoglobin was determined in EDTA blood samples using
reagents for calcium from Bio System Company and for
HbA1c and phosphate from SPINREACT Company.
The means of plasma calcium levels show no significant
difference between all groups studied (diabetic males and
females and also with both males and females healthy
controls) (p>0.05).
The plasma levels of calcium had no correlation with the
duration of diabetes mellitus among both diabetic males and
females.
The means of plasma phosphate levels showed no
significant difference between the diabetic and non-diabetic
male groups and also with the diabetic female group
(p>0.05).
The means of plasma phosphate levels were significantly
reduced in diabetic females when compared with healthy
females (p<0.05).
The plasma levels of phosphate showed insignificant
weak negative correlation with the duration of diabetes in
both; the diabetic male group and the diabetic female
group.
There was no significant difference between the means
of glycated haemoglobin in both the diabetic male and
female groups (p>0.05).
There was a significant weak positive correlation
between the plasma levels of glycated haemoglobin and the
duration of diabetes mellitus in the diabetic female group,
whereas there is no correlation in the diabetic male group.
From the results of the present study it is concluded
that; in Sudanese patients with type 2 diabetes mellitus, the
plasma levels of calcium, phosphate and glycated are not
affect with gender and duration of diabetes.
