Abstract:
A cross-sectional study conducted during the period from March
2011to May 2011, compared the plasma levels of total cholesterol,
triglycerides, high and low density lipoproteins, urate and HbA1c of 52
Sudanese patients with type 2 diabetes mellitus as a test group and 30
apparently healthy (non-diabetic) as a control group. Participants in this
study were from Jabir Abu Elez diabetic center in Khartoum state, Sudan.
The plasma levels of total cholesterol, triglycerides, high and low density
lipoproteins, and urate were measured using commercial reagent kits
from Biosystem Company, whereas HbA1c was measured using a semi
automated method.
The means of the plasma levels of total cholesterol, triglycerides,
low density lipoproteins, urate, and HbA1c% of the diabetic group was
significantly raised when compared to the control group.
The mean of the plasma levels of high density lipoproteins of the
diabetic group was significantly reduced when compared to the control
group.
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In the diabetic group the plasma levels of total cholesterol,
triglycerides, low density lipoproteins, urate and HbA1c show weak
positive correlations with the duration of diabetes and the body mass
index, whereas the plasma level of high density lipoproteins shows a
negative correlation with the duration of diabetes and the body mass
index.
From the results of this study, it is concluded that; diabetes mellitus
is associated with high plasma levels of total cholesterol, triglycerides,
low density lipoproteins, urate, and HbA1c and low plasma levels of
HDL-c. In addition, there are weak correlations between the plasma
levels of total cholesterol, triglycerides, high density lipoproteins, low
density lipoproteins, urate and HbA1c with the duration of diabetes and
body mass index.
