Abstract:
This is a cross- sectional, hospital - based study was carried out to measure the
levels of plasma Zinc and Copper in Sudanese chronic renal failure patients
treated with chronic hemodialysis attending Selma Renal Dialysis Centre,
Khartoum state, during the period from March to July 2011.
Sixty five Sudanese chronic renal failure patients treated with maintenance
hemodialysis; including 40 males (aged 19-76years), and 25 females (aged 16-
70years), were enrolled in this study, also thirty apparently healthy individuals to
serve as control group (aged 20-60 years); including 15 males, and 15 females.
Five ml of venous blood were collected from each participant, the plasma
obtained; Zinc and Copper levels were measured by Atomic Absorption
Spectrophotometer (AAS).
Statistical analysis of the obtained results revealed that; means of plasma levels
of Zinc & Copper was significantly lower among chronic hemodialysed patients
compared to control group (p value for Zinc = 0.000 ,Copper = 0.000) .
In chronic renal failure patients Plasma levels of Zinc & Copper not influenced
by age, sex, or the coexisting diseases. Plasma levels of Zinc were affected by
hemodialysis duration (p value 0.004), but with a weak negative correlation,
where as the plasma levels of Copper not influenced by hemodialysis duration. In
conclusion depletion of plasma Zinc and Copper may contribute to the disturbed
trace elements concentration in hemodialysed patients, and will be consider in the
treatment & follow up of chronic hemodialysed patients to well fitness &better
Life.
