Abstract:
A cross-sectional study conducted during the period form January
2011 to June 2011, compared the plasma levels of total cholesterol,
triglycerides, high and low density lipoproteins of 40 Sudanese patients
with type 1 diabetes mellitus as a test group and 30 apparently healthy
(non-diabetic) as a control group. Participants in this study were from
Omdurman Pediatric hospital in Khartoum state, Sudan. The plasma
levels of total cholesterol, triglycerides, and high and low density
lipoproteins were measured using commercial reagent kits and a
spectrophotometer from Biosystem Company.
The means of the plasma levels of total cholesterol, triglycerides,
and low density lipoproteins of the diabetic group significantly raised
when compared to the control group. (p≤ o.o5)
The mean of the plasma levels of high density lipoproteins of the
diabetic group was significantly reduced when compared to the control
group. (p≤ 0.o5)
In the diabetic group the plasma levels of total cholesterol,
triglycerides, and low density lipoproteins shows weak positive
correlation with the duration of diabetes, whereas the plasma levels of
high density lipoproteins shows a negative correlation with the duration
of diabetes.
From the results of this study, it is concluded that; diabetes mellitus
type 1 is associated with high levels of total cholesterol, triglycerides, and
low density lipoproteins and low plasma levels of high density
lipoproteins.
