Abstract:
This is a cross-sectional study, carried out during the period from
June to September 2012. The objective of this study was to assess
ciprofloxacin resistance among bacteria isolated from patients with
UTI.
133 Urine specimens were collected from patients suspected of
having UTI, attended Omdurman Teaching Hospital. The specimens
were cultured on blood agar and CLED agar for primary isolation of
the causative agents. The identification of the isolated bacteria was
done by colonial morphology, Gram 's stain and biochemical tests.
Ciprofloxacin resistance was assessed by modified Kirby-Bauer disk
diffusion method.
The study results showed that 72 (54.1%) out of 133 specimens
yielded bacterial growth, while the rest 61(45.9%) failed to
demonstrate any bacterial growth. Among the isolates there were 61
(84.7%) Gram –negative and 11 (15.2%) Gram-positive. Bacteria
identified were E. coli 37 (51.4%), Klebsiella pneumoniae 10
(13.8%), Enterococcus faecalis 8 (11.1%), Proteus mirabilis 7 (9.7%),
Pseudomonas aeruginosa 4 (5.6%), Staphyllococcus aureus 3 (4.2%)
and Klebsiella oxytoca 3 (4.2%). Study on the assessment of
ciprofloxacin resistance revealed that the resistance of Klebsiella
pnuemoniae was 7 (70%), Enterococcus faecalis 5 (62.5%), E. coli 23
(62.2%), Pseudomonas aeruginosa 2 (50%), and Proteus mirabilis 1
(28.6%).
However,
there
was
no
resistance
Staphylococcus aureus and Klebsiella oxytoca.
The study concluded that the resistance to ciprofloxacin was high
Klebsiella
.i.e
Pseudomonas
uro-pathogens
,coli
.E
important
,faecalis
most
Enterococcus
the
among
,pnuemoniae
aeruginosa and Proteus mirabilis. Further studies are required to
.validate this result
