Effects of Guru (Cola nitida) on Drug Metabolizing Enzymes in Rats

dc.contributor.author	Ahmed , A.M.
dc.contributor.author	Mohamed , O. S. A.
dc.contributor.author	Homeida , Mohamed .A.M.
dc.date.accessioned	2017-04-30T06:53:01Z
dc.date.available	2017-04-30T06:53:01Z
dc.date.issued	2012
dc.identifier.citation	Ahmed , A.M. . Effects of Guru (Cola nitida) on Drug Metabolizing Enzymes in Rats / A.M. Ahmed , O. S. A. Mohamed , Mohamed .A.M. Homeida .- Journal of Science and Technology .- vol 13 , no 2 .- 2012 .- article .	en_US
dc.identifier.issn	ISSN 1605-427X
dc.identifier.uri	http://repository.sustech.edu/handle/123456789/16863
dc.description	article	en_US
dc.description.abstract	The objective of this study was to investigate the effect of guru on drug metabolizing enzymes in rats. Guru at a dose of 100mg/kg administered orally to rats caused induction of hepatic microsmal mixed function oxidase , but at the dose of 200 and 400 mg/kg inhibited the drug metabolizing enzymes compared to controls that were given rat diet . It is concluded that guru may produce pharmacological effects at the dose of 100mg/kg and toxicological effects at higher doses.	en_US
dc.description.sponsorship	Sudan University of Science and Technology	en_US
dc.language.iso	en_US	en_US
dc.publisher	Sudan University of Science and Technology	en_US
dc.subject	Aminopyrine-N-demethylase , Aniline-4-hydroxylase, UDP-glucuronyltransferase Glutathione-S-tranferase, Cytochrome p-450	en_US
dc.title	Effects of Guru (Cola nitida) on Drug Metabolizing Enzymes in Rats	en_US
dc.type	Article	en_US