Abstract:
Stems of Detarium senegalense were screened for secondary metabolites.
Phytochemical screening revealed the presence of steroids, triterpenes,
flavonoids, tannins, saponins , anthraquinones and cyanogenic glycosides.
Fractionation by paper chromatography gave three flavonoids : I,II and III.
Different fractions (chloroform,ethyl acetate and n-butanol) were evaluated ,
in vitro, for antimirobial activity against six standard human pathogens :
Bacills subtilis, Staphylococcus auerous , Escherichia coli, Pseudomonas
aeruginosa, Candida albicans and Aspergillus niger and significant results
were obtained.
