Abstract:
In recent years the antimicrobial resistance increases and this results
in increase rate of infectious diseases. The objective of this study was
to assess antimicrobial resistance in patients with pneumococcal
infection.
Sputum and CSF specimens were collected from patients suspected to
have pneumococcal infections. The patients attended to Omdurman
Pediatrics Emergency Hospital, Al-sh’ab Hospital, Military Hospital and
Gaafer Ebn Awf Hospital.
The specimens were cultured on blood agar and chocolate agar for
primary isolation of the causative agent. The identification of the
isolated bacteria was done by colonial morphology, Gram’s stain and
biochemical tests. Antimicrobial resistance was assessed for isolate by
modified Kirby-Bauer disk diffusion method.
The results revealed that S. pneumoniae was isolated from 27 (10.8%)
out of 250 specimens. The rate of resistance among S. pneumoniae
was 40.7% to penicillin followed by tetracycline, 18.5%; ciprofloxacin,
14.8%; erythromycin, 14.8% and chloramphenicol, 11.1%.
The study was conducted that the resistance of S. pneumoniae for
penicillin is too high and the chloramphenicol is effective to most
pneumococcal isolates. Further studies are required to validate these
results.
