Abstract:
This is a case control study, conducted in Omdurman locality from February to June 2015, to determine CBC values of pregnant women at first trimester. Eighty pregnant women as cases and forty non pregnant women as controls. Pregnant women were informed about the study and agreed for participation. A questionnaire was designed to collect demographic data about the study group, tow and half ml EDTA venous blood was taken and analyzed automatically (Sysmex KX – 21N) to measure CBC, the data was analyzed using SPSS computer programme.
The results indicated that: in pregnant woman the Hct(35.0±4.2%), MCV(81.1±6.90fl) increase significantly (p.value0.0,0.0 respectively) while MCHC(34.2±1.95%), MPV(9.5±1.20fl) decease significantly (p.value0.00, 0.03 respectively), RDWSD(40.5±5.93fl), TWBCs (7.3±2.7×109/L), neutrophil absolute (4.6±2.8×109/L), platelet count (276±71.2×109/L), PDW(13.2±2.65) increase insignificantly (p.value 0.1, 0.6, 0.8, 0.8,0.4 respectively) Hb (12.0±1.41g/dl), RBCs (4.36±0.53×1012/L), MCH(27.4±2.51pg), lymphocytes percentage(33.5±12.9%),neutrophils percentage (58.6±13.6%) decease insignificantly (p.value0.7,0.9,0.9,0.6,0.4) but there is no difference in lymphocytes absolute (2.2±0.86×109/L) compared to control.
Supplementation intake and regular clinical follow up during pregnancy significantly increase Hct, MCV, MCH, PDW and MPV (p≤ 0.01); however, history of abortion and duration of pregnancy did not significantly affect CBC.
We concluded that there was significant increased in Hct, MCV (P=0.00) and significant decreased in MCHC and MPV (P=0.00) in pregnant women when compared with non-pregnant control.
