Changes of Some Haematological Parameters in Chronic Renal Failure patients after

Abstract

This study was conducted at Haemodialysis Unit in Armed Forces Medical Services Hospital, Omdurman, during the period from February 2015 to May 2015 to evaluate Haematologial Changes in Chronic Renal Failure patients undergo Haemodialysis. Blood samples were collected-in EDTA- from 100 chronic renal failure patients undergoing hemodialysis before and after dialysis sessions. A questionnaire was used to collect some information about the patients and The samples were tested using automated machine (Sysmex KX-21N). Males comprises 62% of patients who were aged 20 to 80 years. The results from the patients undergo Hemodialysis showed that the mean of White Cells count pre Hemodialysis were (5.03 /µI ±1.5), while the mean of White Cells count post Hemodialysis were (5.63 /µI ±2.1) and this indicates significant increase after Hemodialysis (p.value 0.000). The mean of Red Cells count pre Hemodialysis were (3.26 /µI ±0.6), while the mean of Red Cells count post Hemodialysis were (3.46 /µI ±0.7) and this indicates significant increase after Hemodialysis (p.value 0.000). The mean of Hemoglobin pre Hemodialysis were (9.5g/dl ±2.2), while the mean of Hemoglobin post Hemodialysis were (10.2 g/dl ±2.0) and this indicates significant increase after Hemodialysis (p.value 0.000). The mean of Packed Cell Volume pre Hemodialysis were (30.7% ±6.3), while the mean of Packed Cell Volume post Hemodialysis were (32.5% ±6.6) and this indicates significant increase after Hemodialysis (p.value 0.000). The mean of Mean Cell Volume pre Hemodialysis were (92.5 fl ±9.9), while the mean of Mean Cell Volume post Hemodialysis were (93.1 fl ±10.1) and this indicates insignificant increase after Hemodialysis (p.value 0.59). The mean of Mean Cell Hemoglobin pre Hemodialysis were (29.7 pg ±2.0), while the mean of Mean Cell Hemoglobin post Hemodialysis were (29.3 pg±3.3) and this indicates insignificant decrease after Hemodialysis (p.value 0.15). The mean of Mean Cell Hemoglobin Concentration pre Hemodialysis were (31.7% ±1.1), while the mean of Mean Cell Hemoglobin Concentration post Hemodialysis were (31.5% ±1.2) and this indicates significant decrease after Hemodialysis (p.value 0.03). The mean of Platelets count pre Hemodialysis were (1843/µI ±68.1), while the mean of Platelets count post Hemodialysis were (1883/µI ±74.6) and this indicates insignificant increase after Hemodialysis (p.value 0.09). The mean of Lymphocytes count pre Hemodialysis were (1.18 0.7± %), while the mean of Lymphocytes count post Hemodialysis were (1.190.8± %) and this indicates insignificant increase after Hemodialysis (p.value 0.97). The mean of Mixed cells count pre Hemodialysis were (0.57%), while the mean of Mixed cells count post Hemodialysis were (0.61%) and this indicates insignificant increase after Hemodialysis (p.value 0.264). The mean of Neutrophil count pre Hemodialysis were (3.3%), while the mean of Neutrophil count post Hemodialysis were (3.9%) and this indicates significant increase after Hemodialysis (p.value 0.000).