Abstract:
Cigarette smoking is wildly spread throughout the world and theeffects of smoking on human health are serious.
This is a case control study was done in Khartoum area during March-June2015, to evaluate serum iron and total iron binding capacity levels in smokers.
Seventy smokers were selected as test group and fifty non smokers as control group (age was matched), blood specimen were collected from both groups and serum iron and serum TIBC concentration were determine by using auto analyzer (Cobas).
Statistical analysis was done by using SPSS, the results showed a significant increase in mean of serum iron and a significant decrease in mean of serum TIBC concentrations in smoker when compare to non smoker(control )group P. value =(0.000),(0.000) respectively .
The results also showed a significant positive correlation between number of cigarettes per day and serum iron concentration, and a significant negative correlation between number of cigarettes per day and serumTIBC concentration (serum iron concentration P=0.000, r=0.604),(serum TIBC P=0.000, r= - 0.499).
Statistical analysis also showed a significant positive correlation between duration of cigarettes per year and serum iron concentration, and a significant negative correlation between duration of cigarettes per year and serumTIBC concentration (serum iron p. value=0.000, r=0.797),(serum TIBC p. value=0.000, r= - 0.410).
The study Results revealed that smoking habit lead to significant elevation of serum iron and significant decreasing in serum TIBCcompared tonon smokers.Increase in serum iron is proportional with duration of smoking per years and number of cigarettes smoked per day, also the serum iron concentration is significant positive correlation with duration of smoking per years and number of cigarettes smoked per day. Decrease in serum total iron binding capacity is inversely relation with duration of smoking per years and number of cigarettes smoked per day, also the serum total iron binding capacity concentration is significant negative correlation with duration of smoking per years and number of cigarettes smoked per day.
