MESUREMENT OF T1 AND T2 RELAXATION TIME IN BRAIN TISSUE USING MRI 1.5 TESLA

Abstract

The relaxation times T1 and T2 plus the proton density (ρ) are the quantities Likely to give the best tissue discrimination in nuclear magnetic resonance imagining (NMR). These parameters play a pivotal role in determining tissue contrast, which allows clinicians to clearly see the details of tissue structure, including soft tissue, and to distinguish normal from diseased tissue in order to diagnose and track the progress and treatment of disease. In this study relaxation times T1 and T2 measurements were performed using MRI system operating at 1.5T magnet strength. T1 and T2 values were calculated from carefully selected regions of interest representing gray matter, white matter, fat and cerebrospinal fluid (CSF) of human brain. The result shows a difference in T1 and T2 values for the different type of tissue. These differences are found to be responsible for the different tissue contrast in MRI and consequently the ability of this imaging modality to characterize the different type of tissue for diagnostic assessment.