Frequency of Sickle Cell Trait among the Relatives of Patients Referred to El gadrif Hospital

Abstract

This was prospective and analytic study aimed to detect the frequency of sickle cell trait among the relatives of patients who referring to El gadarif hospital in El gadarif state . The study was conducted in the period between October 2008 and February 2009. Hundred samples were collected into EDTA blood containers from relatives of patients of sickle anemia . All samples were investigated for CBC by use of blood analyzer mysic18 , sickling test and Hb electrophoresis to detect type of Hb . Data were analyzed by use of statistical package program (SPSS) . The results were showed that79% of samples were (AS) , and the remaining were (AA). The highest percentage of sickle cell trait was found in El hawsa tribe with frequency of (33% ) ,followed by Falata (29%), Barno (11%), Foor (10 %) , Messrria (6%) and the lowest percentage was found in Begereia tribe with frequency of( 3%). Most of sickle cell trait were found in October area with frequency of followed by Kajara ( 37%), and Darawish with frequency of (11%), Moasasat (8%) ,Mosa (5%),Metar , Salamet albeh and Abaker J (4% ) and the lowest percentage was found in Ambasa , Shashol and Doka ( 2%) . Also the study showed that mean of Hb was 11.2 g/dl , RBCs count was 4.5×10 9/L ,WBCs count was 6.6×109/L , PLts count was 306×109/L , PCV 35% , MCV 84 fl , MCH 26 pg and MCHC 32 % The study showed that 73% of samples were normocytic normochromic and remaining were microcytic hypochromic .