Abstract:
This was prospective and analytic study aimed
to
detect
the
frequency of sickle cell trait among the relatives of patients who
referring to El gadarif hospital in El gadarif state . The study was
conducted in the period between October 2008 and February
2009.
Hundred samples were collected into EDTA blood containers
from relatives of patients of sickle anemia . All samples were
investigated for CBC by use of blood analyzer mysic18 , sickling
test and Hb electrophoresis to detect type of Hb . Data were
analyzed by use of statistical package program (SPSS) . The
results were showed that79% of samples were (AS) , and the
remaining were (AA).
The highest percentage of sickle cell trait was found in El hawsa
tribe with frequency of (33% ) ,followed by Falata (29%), Barno
(11%), Foor (10 %) , Messrria (6%) and the lowest percentage was
found in Begereia tribe with frequency of( 3%). Most of sickle cell
trait were found in October area with frequency of
followed by
Kajara
( 37%),
and Darawish with frequency of (11%),
Moasasat (8%) ,Mosa (5%),Metar , Salamet albeh and Abaker J
(4% ) and the lowest percentage was found in Ambasa , Shashol
and Doka ( 2%) .
Also the study showed that mean of Hb
was 11.2 g/dl , RBCs count was 4.5×10 9/L ,WBCs count was
6.6×109/L , PLts count was 306×109/L , PCV 35% , MCV 84 fl ,
MCH 26 pg and MCHC 32 %
The study showed that 73% of
samples were normocytic normochromic and remaining were
microcytic hypochromic .
