Frequencies of ABO and Rhesus blood group antigens and phenotypes among Al Halanga Sudanese Ethnic Group

Abstract

This prospective and analytical study, aimed to determine the frequency of ABO, Rh antigen, and phenotypes, among Halanga Sudanese Ethnic group. Also aims to establish ABO, Rh blood group baseline data for this Sudanese tribe to determine the similarity between this tribe and other Sudanese tribes which will be useful in the blood transfusion. The study was conducted during three months (April to July, 2007), Following informed consent, a total of hundred venous blood samples were collected from unrelated individual into 2.5 ml EDTA containers. All samples were tested for ABO and for common Rhesus antigens by using the slide agglutination techniques, and immune-diffusion gel technique. The antigens and phenotypes were determined. Similarities between this tribe and other Sudanese tribes and with other countries were calculated using Jaccard's coefficient of similarities. The results obtained showed that, The O group was most common frequently occurred (47% ) , followed by group A ( 28%), group B was found ( 22% ) and least common was group AB ( 3%). The e, c, and the D antigens were the commonest alleles detected with frequencies of 96%, 91% and 82%, respectively. The C and the E antigens were the least frequent with 40% and 15% frequencies respectively. There was a marked similarities between the Sudanese tribes that lived in same geographical area this could be due to intermarriage , while the difference that seen in some tribes could be most probably due to the wandering nature of these tribes.