Determination of Some Blood Coagulation Parameters among Pre-eclampsia Pregnant Women Attending Omdurman Maternity Hospital

Abstract

This is a cross sectional analytical study conducted in Omdurman maternity hospital during period march 2012 to June 2012; the study was included 50 pregnant women with pre-eclampsia were selected randomly with age ranged between (18- 37) years. 25 healthy pregnant women of the same age range enrolled as control group. Every female interviewed through especial questionnaire to collect historical data, citrate blood sample was collected from each pre-eclampsic pregnant woman, and citrated poor plasma was immediately harvested and analyzed, using automated coagulometer for prothrombin time ( PT ), activated partial thromboplastin time ( APTT), and fibrinogen level. The mean of PT values of the study group was (13 sec) and the controls was (13 sec), the mean of APTT value study group was (51 sec) and the controls was (30 sec), the mean of fibrinogen level of the study group was (476mg/dl) and the controls was (296mg/dl). The study results revealed that there was insignificant value for prothrombin time of pre- eclampsic women (P value >0.05) whoever high with significant increased in activated partial thromboplastin time and fibrinogen level of pre- eclamsic women compared to normal control mean level (p.value < 0.000).