Comparison of Glucose Results Obtained by Accu-Chek Active Glucometer (Dry Chemistry) to Glucose Oxidase (Method (Wet Chemistry

Abstract

Background: Abnormal blood glucose levels are common in ill patients with diabetes and increase the risk of complications such as infection, metabolic problems, and/or cerebral damage. Frequent monitoring of blood glucose levels and aggressive management of hyperglycemia can decrease these complications. Although laboratory analysis is the most accurate method for evaluating glucose levels, because of cost and time delays; bedside point-of-care (POC) testing is often used to determine glucose levels when frequent monitoring of glucose is important. The aim of this study was to compare glucose results obtained by Accu- Chek Active glucometer (dry chemistry) to glucose oxidase method (wet chemistry). Method: Point of care values were compared with laboratory values in 60 diabetic patients who attended Alban Jaded Educational Hospital, and Diabetic and Endocrine Centre in Khartoum North, for routine follow up during the period from 18.11-9.12. First capillary whole blood samples were analyzed by glucometer (Accu- Chek Active), then venous blood samples were collected for plasma glucose analysis. Results: This study showed that mean capillary whole blood glucose levels, measured in Accu- Chek Active glucometer (dry chemistry), were not significantly different from mean laboratory plasma glucose levels as measured by glucose oxidase method (wet chemistry) using independent-t test (P-value= 0.341). Conclusion: Glucose values of point of care samples were not differ significantly from specific laboratory method values, therefore, the glucometer Accu-Chek Active can be used in the Sudan for monitoring of blood glucose level in diabetic patients, considering the appropriate use of the device.