Complete Blood and Reticulocyte Count among Malaria Patients in Khartoum State

Abstract

Malaria is major causes of morbidity and mortality in the tropical countries, effect in hematological variables as outcome. The aim of study to measure of complete blood count which included RBCs count, Hb, HCT, MCV, MCH, MCHC , WBCs count and differential, platelet count and platelet indices included PDW and MPV , also measure of reticulocyte count among patients with malaria. This is a cross -sectional descriptive study done in Khartoum state. Fifty blood samples were collected from individual with malaria and twenty five blood samples collected from healthy individual as control drained into the sterile EDTA containers using automated hematology analyzer (sysmex KX-2IN). The study explain that mean value of RBCs in patients with malaria was (4.1 ×1012/L ± 0.8) ,mean value of hemoglobin ( 11.5 × g/dl ± 2.6),mean value of HCT(36.9% ± 7.6) , mean value of MCV, MCH and MCHC(88.7 fl ± 7.5 ,27.7 pg ± 3.4 and 31.1 % ± 2.0) respectively, mean value of reticulocyte count ( 1.48 % ± 0.55), also explain mean value of WBCs (6.69×109 /L ± 3.9 )and differential (neutrophil 4.0×109 /L ± 2.7 ,lymphocyte 2.1×109 /L ±1.9, monocyte 0.5×109 /L ±0.32 and eosinophil 0.15×109 /L ± 0.08 ). And explain mean value of platelet count (137 ×109 /L ± 97) and platelet indices (PDW 14.1 ± 3.6, MPV 10.1± 1.4 ) . The study explain the main type of anemia in patients with malaria was normocytic normochromic anemia. The study done in male (68%) than female(32%) and most of them in age group 26 to 39 years. The study reveled that , there was no change in (MCV, MCH , MCHC , reticulocyte count ,WBCs and differential , but they were decreased significantly in (RBCs, Hb, HCT and PLT count ) and increased significantly in platelet indices (MPV and PDW).