Estimation of Bone Scientigraphy Accuracy in Diagnosis of Multiple Myeloma with bone scientigraphy

Abstract

Multiple myeloma is one of common cancer in Sudanese people and it’s once of common cause of cancer death and want good diagnosis to begin the first road to kill this disease. Therefore evaluation of multiple myeloma with bone scientigraphy it’s crucial. Hence the main objective of this study is to evaluate the multiple myeloma by using bone scientigraphy with 99mTc-MDP. The data of this study was collected from 50 patients of multiple myeloma attending to RICK (Radiation and Isotope Center of Khartoum) and RICA (Radiation and Isotopes Center of Al-jazeera). The procedure done by taking 25 mCi of Tc-99m MDP utilizing 3 hour delayed regional planar images on a Mediso SPECT (Single Photon Emission Computed Tomography) body scan and get all last investigations done as laboratory tests, bone marrow aspiration, and X-ray from the patient’s file. The bone scientigraphy analysis to show the accuracy of bone scientigraphy by comparing with X-ray and was comparing the bone scientigraphy with other investigations to evaluate the bone scientigraphy. The results of this study showed that there is a high incidence multiple myeloma in male than female almost two folds, were 32 (64%) male and 18 (36%) female. The age of the patient ranged from 27-80 years with a higher incidence of multiple myeloma in the age ranged between 59 to 80 years (48%). The bone scientigraphy demarcated 32 (64%) as have multiple myeloma, while X-ray reveals 44 (88%) patients as having typical characteristics of multiple myeloma out of 50 patients. Laboratory test result for multiple myeloma patients which include HB, WBC, Platelets and calcium in general they are within the normal limits.