Evaluation of Endometrial Thickness in Breast Cancer Patients Treated by Tamoxifen using Ultrasonography

Abstract

This study aimed to identify and evaluate the endometrial thickness of breast cancer patient whose treated by tamoxifen using ultrasonography . According to the data was collected from 50 patients at diagnostic ultrasound department at many centers in Khartoum state , during the period from first September to fifteenth of October .The investigated by ultrasound to measure their endometrial thickness. The data was analyzed by using statistical packages for social sciences (SPSS) under windows using T-test between age of patient, duration time of taking tamoxifen, endometrial thickness before and after treatment. The results of study gived us relationship between the duration time of taking tamoxifen and endometrial thickness of breast cancer patient ,when there is long time of taking tamoxifen there is big thickness of endometrium . It concluded that Tamoxifen significantly increases the risk of developing abnormally thickened endometrium in breast cancer patients. There is, thus, a true need for gynaecologic surveillance in such patients to early detect neoplastic change of endometrium that may arise as a result of tamoxifen use.