Abstract:
A descriptive cross-sectional study was conducted to evaluate Prolactin level in
women with breast cancer, and to correlate serum Prolactin level with risks factors of
breast cancer.
The study included, fifty patients histopathologicaly diagnosed with breast cancer and forty
healthy individuals as control group, the study was carried out in Radio Isotope Centre
Khartoum (RICK), during the period from April to December 2013. Serum prolactin level in
both patients and control group was estimated using Micro-practical Enzyme Immunoassay
technology (MEIA), data analyzed using t-test and Pearson correlation in SPSS computer
program.
The results showed that serum prolactin level is significantly increased in patients
versus Controls with (P-value 0.001), also the results showed significant increase in
the mean serum prolactin level among patients with breast cancer >40 years
(postmenopausal) compared with <40 years (premenopausal) with (P-value 0.003).
The study concluded that Serum PRL levels were higher in women with breast cancer
than the controls, prolactin level positively correlated with age, stage of the disease
and there was no correlation with the family history.
