Antibiotic Sensitivity and Resistance of some Pathogenic Bacteria Isolated from Clinical Specimens

Abstract

This study has been carried out in Khartoum state during the period October 2005 to February 2006. The study has evaluated the activity of Gentamicin, Ciprofloxacin, Ceftazidime Impenem and amikacin against Pseudomonas aeruginosa, Tetracycline, Penicillin, Ciprofloxacin Gentamicin, against staphylococcus aureus, and isolates of Enterobacteriaceae against Nalidixic acid, Nitrofurantoin, Gentamicin, Ciprofloxacin, Tetracycline, except for Proteus spp. Specimens were collected from different hospital in Khartoum state, including Khartoum Teaching Hospital 131 (34.5%) Medical Military Hospital 76 (20%), Ibrahim Malik Hospital 12 (3.2%), National Health Laboratory 49 (12.8%) & ENT Hospital 122 (29.5%) Different types of bacteria were isolated from those specimens including Staph aureus 37 (15%), E. coli 70 (28.5%) , Klebsiella Pneumoniae 15 (6.1%), Proteus spp 57 (23.2%) and Pseudomonas aeruginosa 67 (27.2%). The most effective antibiotic for Pseudomonas aeruginosa were Ceftazidime and impenem because the resistant rate was (0%) followed by Amikacin, Gentamicin then Ciprofloxacin. For E. coli the most effective antibiotic is Gentamicin because the resistant rate is (7.7%). Nitrofurantion is better than Nalidixic acid for urinary isolates. For Klebsiela Pneumoniae isolates Gentamicin and Nitrofurantoin are the most effective antibiotics because of their low resistant rate (20%) for both. Staph aureus infections Gentamicin and Ciprofloxacin are the most suitable antibiotics because they have resistant rate of (5.6%) and (10.8%) respectively.