Abstract:
This study has been carried out in Khartoum state during the period October
2005 to February 2006.
The study has evaluated the activity of Gentamicin, Ciprofloxacin,
Ceftazidime Impenem and amikacin against Pseudomonas aeruginosa,
Tetracycline, Penicillin, Ciprofloxacin Gentamicin, against staphylococcus
aureus, and isolates of Enterobacteriaceae against Nalidixic acid,
Nitrofurantoin, Gentamicin, Ciprofloxacin, Tetracycline, except for Proteus
spp.
Specimens were collected from different hospital in Khartoum state,
including Khartoum Teaching Hospital 131 (34.5%) Medical Military
Hospital 76 (20%), Ibrahim Malik Hospital 12 (3.2%), National Health
Laboratory 49 (12.8%) & ENT Hospital 122 (29.5%) Different types of
bacteria were isolated from those specimens including Staph aureus 37
(15%), E. coli 70 (28.5%) , Klebsiella Pneumoniae 15 (6.1%), Proteus spp
57 (23.2%) and Pseudomonas aeruginosa 67 (27.2%).
The most effective antibiotic for Pseudomonas aeruginosa were Ceftazidime
and impenem because the resistant rate was (0%) followed by Amikacin,
Gentamicin then Ciprofloxacin. For E. coli the most effective antibiotic is
Gentamicin because the resistant rate is (7.7%). Nitrofurantion is better than
Nalidixic acid for urinary isolates. For Klebsiela Pneumoniae isolates
Gentamicin and Nitrofurantoin are the most effective antibiotics because of
their low resistant rate (20%) for both. Staph aureus infections Gentamicin
and Ciprofloxacin are the most suitable antibiotics because they have
resistant rate of (5.6%) and (10.8%) respectively.
