Determination of Hematological Parameters in Malnourished Children in Khartoum, Omdurman and Albulk Pediatric Hospitals

Abstract

This was a hospital base and analytical study, to determine Hematological parameters among Malnourished Children below 5 years. Fifty Malnourished Children and twenty apparently healthy similar to study group served as a controls group was used. Every participant informed about the study, excepted outcomes and agreement of participation was obtained. A questionnaire was used to collected information about Study group, age, sex, weight, height. Family number, interval between pregnancy immunization, education and economical status of parents. 5ml of vinous blood was taken from the Study group, 2.5 ml in EDTA anticoagulant container for CBC and 2.5ml in plain container for Serum iron and Serum ferritin. Fully automated Sysmex Kx21N was used to determine CBC, and A25Biosystem was used for serum iron and serum ferritin. Computerize statistical package for social science (version 11.5) used for data processing. Study group was divided according to sex, which males were 46% and females were 54%. Age groups <18 month was (58%), 18-36 month was (34%) and >36 month was (8%). According to type of malnutrition Marasmus was comprised 41%, Kwash 6% and Mrasmic-kwash was 3%. Results showed that all malnourished children were anemic (100%). Mean value of hemoglobin MCV, MCH, MCHC and hematocrit decreased significantly compared to control (P value 0.000), the means were 8.8, 72, 22.5, 30.9 and28.7 respectively. WBCs and PLTS were significantly increased compared to control (p value 0.000); the mean was 12 x103/ul and 570 x103/ul respectively. Serum iron and serum ferritin was significantly decreased compared to control (p value 0.000); the mean was 43.89 ug/dl and 17.882 ug/l respectively.