Abstract:
This study was carried out to measure serum total cholesterol level and
Aspartate transaminase (AST)activity in the blood male of
Sudanese
with cigarette smokers.
Fifty samples were collected from cigarette smokers without any disease
in period between May –September 2013.
Fifty smokers between the age 18-86 years and with duration ranging
2-35years .two and half of blood samples were taken from these cigarette
smoker’s as well as 50 male non smokers also in this study roll all the
participant were randomly select present social status.
Samples were collected from non cigarette smoker’s subject as control
group to measure serum total cholesterol level by using colorimeter and
Aspartate transaminase (AST) activity By using sepectrophotometer All
results were analyzed using statistical of package social science
)
SPSS( computer program.
The study showed that a significant elevation of serum total cholesterol
level in cigarette smokers (211±8.3) mg/dl when compared to
non
cigarette smokers (154+5.4) mg/dl with P.value (0.008) The study also
showed that Aspartate transaminase (AST)activity was significant ly
increased in blood of smokers compared to control being (38±10) μ/l
(23±5.4) μ/l with P.value (0.001) .
The study indicates that the duration of cigarette smokers
significantly increased
has
the level of cholesterol and Aspartate
transaminase(AST) activity with p.value (0.007) .
The study indicates that the number of cigarette /day has significant
difference between serum total cholesterol level. Mean 2-10 cigarette/day
(209±5.7) mg/dl more than 11cigarette /day (224±8.4) mg/dl
p.value =0.0000
The study indicates that serum total cholesterol level is not significantly
affected by age of cigarette smokers there is no different in value in total
cholesterol level between two age group in this study Mean in 18- 45
years (211±5.5) mg/dl 46- 85years (209±4.1) mg/dl with p.value (0.34) .
The enzyme Asparate transaminase (AST)activity was no significant
differ the value was regret to duration of smoker age the smoker number
cigarette smokers.
Person correlation show
correlation
that there was significant weak positive
between the duration of cigarette smokers and the level of
Serum cholesterol and r = 0.065 with
p.value (0.65) no significant
between duration and total cholesterol level cigarette smokers also no
correlation between age of smokers number of smoker .
Aspartate transaminase activity in other hand also show no correlation of
statistical significance with duration of smoker ,age smoked and number
of smokers the out came of this study total cholesterol level and Aspartate
transaminase (AST)activity enzyme significance increase in blood of the
smokers with remarkable affect duration of smoker and number of
cigarette smoked.
Condition that may increase the risk of cardiovascular disease and
atherosclerosis.
