Plasma Magnesium and Phosphorus Levels among Patients with Metabolic Syndrome in Khartoum State

Abstract

Metabolic Syndrome is a serious medical condition with increase risk of multiple cancers, has effects on the life quality. It is a problem found all over the world and Sudan. Also it is fatal unless controlled and treated properly. A case control study conducted to compare the plasma level of magnesium and phosphorus of 50 randomly selected patients with metabolic syndrome as case group(age range 40-80 years) and 50 apparently healthy as control group (matched age and gender). Participants in this study were from Almotakamel center and Zinam Specialist Hospital in Khartoum state, Sudan. The plasma level of magnesium and phosphorus were measured using Mindray BS-200 (full automation instrument). The results were analyzed using statistical package for social science (SPSS version 16) computer program. The study showed that, metabolic syndrome most common among age group (61-70) years (40%) and most abundant in females (62%) than males (38%). The study showed that, there were significant decreased in mean of magnesium and phosphorus, while the mean of Waist Circumference and Body mass index (BMI) significantly increased in cases than control group (1.98±1.22 than 2.15±0.33mg/dl, P-value 0.000), (2.55±1.12 than 3.13±0.76mg/dl, P-value 0.003), (107.8±9.83 than 99.58±11.69cm, P-value 0.000) (30.02±5.05 than 27.42±4.59kg/m2, P-value 0.008) respectively. There was insignificant difference in the mean of plasma magnesium and phosphorus level between males and females of metabolic syndrome patients group (2.15±1.62 versus 1.66±0.62 P-value 0.165) (2.51±1.07 versus 2.62±1.42 P-value 0.730) respectively. The study also showed, there was no correlation between plasma level of magnesium, BMI and age(r= 0.096, P-value= 0.508) (r= 0.058, P-value =0.687) respectively. The study also showed that, there was no correlation between plasma level of phosphorus, BMI and age(r= -0.199, P-value=0.166) (r= -0.221, Pvalue= 0.122) respectively. The present study concluded that: Patients with metabolic syndrome had lower concentration of magnesium and phosphorus, also metabolic syndrome is more common in females than males and more frequent in elderly.