Abstract:
Metabolic Syndrome is a serious medical condition with increase risk of
multiple cancers, has effects on the life quality. It is a problem found all
over the world and Sudan. Also it is fatal unless controlled and treated
properly.
A case control study conducted to compare the plasma level of magnesium
and phosphorus of 50 randomly selected patients with metabolic
syndrome as case group(age range 40-80 years) and 50 apparently healthy
as control group (matched age and gender). Participants in this study were
from Almotakamel center and Zinam Specialist Hospital in Khartoum state,
Sudan. The plasma level of magnesium and phosphorus were measured
using Mindray BS-200 (full automation instrument). The results were
analyzed using statistical package for social science (SPSS version 16)
computer program.
The study showed that, metabolic syndrome most common among age
group (61-70) years (40%) and most abundant in females (62%) than males
(38%).
The study showed that, there were significant decreased in mean of
magnesium and phosphorus, while the mean of Waist Circumference and
Body mass index (BMI) significantly increased in cases than control group
(1.98±1.22 than 2.15±0.33mg/dl, P-value 0.000), (2.55±1.12 than
3.13±0.76mg/dl, P-value 0.003), (107.8±9.83 than 99.58±11.69cm, P-value
0.000) (30.02±5.05 than 27.42±4.59kg/m2, P-value 0.008) respectively.
There was insignificant difference in the mean of plasma magnesium and
phosphorus level between males and females of metabolic syndrome
patients group (2.15±1.62 versus 1.66±0.62 P-value 0.165) (2.51±1.07
versus 2.62±1.42 P-value 0.730) respectively.
The study also showed, there was no correlation between plasma level of
magnesium, BMI and age(r= 0.096, P-value= 0.508) (r= 0.058, P-value
=0.687) respectively.
The study also showed that, there was no correlation between plasma
level of phosphorus, BMI and age(r= -0.199, P-value=0.166) (r= -0.221, Pvalue=
0.122) respectively.
The present study concluded that:
Patients with metabolic syndrome had lower concentration of magnesium
and phosphorus, also metabolic syndrome is more common in females
than males and more frequent in elderly.
