High Sensitive C-reactive Protein, Magnesium and Lipid Profile Among non-diabetic, non-hypertensive Sudanese Smokers. (A study in Khartoum State)

Abstract

Background and Aim: Cigarette smoking is a classical and a major risk factor in the development of several diseases with an inflammatory component, including cardiovascular disease, chronic obstructive pulmonary disease, and dyslipidemia. The aim of this study to evaluate the plasma levels of high sensitive c-reactive protein, magnesium and lipid profile in smoker’s subjects. Materials and methods: This was descriptive cross-sectional study conducted during the period from April to December 2018, eighty Sudanese individual were included in this study as case, plasma High sensitive c-reactive protein (HS-CRP) was measured by using latex immune turbidymetric method, plasma lipid profile and plasma magnesium were estimated by chemical detection method using photometer, the data obtained was analysis by using SPSS. Results: study showed mean of plasma high sensitive c-reactive protein (HS-CRP), was insignificant increase in smokers when compared to reference value with p value > 0.05, where means of plasma magnesium, Total cholesterol (T.C), triglyceride (TG), High density lipoprotein (HDL-C) and low density lipoprotein cholesterol (LDL-C) were significantly decrease among smokers’ subject when compared to reference values with p value < 0.05. According to duration of smoking, study showed there were significant increase in means of HS-CRP, Total cholesterol, Triglyceride, and LDL-c where significant decrease in means of magnesium and HDL-c with p value < 0.05. Conclusion: The study concludes that, smokers had increase level of HS-CRP, total cholesterol and LDL-C, and decrease in both magnesium and HDL-C levels when increase duration of smoking.