Abstract:
Background and Aim: Cigarette smoking is a classical and a major risk factor in
the development of several diseases with an inflammatory component, including
cardiovascular disease, chronic obstructive pulmonary disease, and dyslipidemia.
The aim of this study to evaluate the plasma levels of high sensitive c-reactive
protein, magnesium and lipid profile in smoker’s subjects.
Materials and methods: This was descriptive cross-sectional study conducted
during the period from April to December 2018, eighty Sudanese individual were
included in this study as case, plasma High sensitive c-reactive protein (HS-CRP)
was measured by using latex immune turbidymetric method, plasma lipid profile and
plasma magnesium were estimated by chemical detection method using photometer,
the data obtained was analysis by using SPSS.
Results: study showed mean of plasma high sensitive c-reactive protein (HS-CRP),
was insignificant increase in smokers when compared to reference value with p value
> 0.05, where means of plasma magnesium, Total cholesterol (T.C), triglyceride
(TG), High density lipoprotein (HDL-C) and low density lipoprotein cholesterol
(LDL-C) were significantly decrease among smokers’ subject when compared to
reference values with p value < 0.05.
According to duration of smoking, study showed there were significant increase in
means of HS-CRP, Total cholesterol, Triglyceride, and LDL-c where significant
decrease in means of magnesium and HDL-c with p value < 0.05.
Conclusion:
The study concludes that, smokers had increase level of HS-CRP, total cholesterol
and LDL-C, and decrease in both magnesium and HDL-C levels when increase
duration of smoking.
