Characterization of Hippocampus in Sudanese using MRI

Abstract

This is cross- sectional analytic study done to describe the hippocampus among Sudanese population using magnetic resonance imaging (MRI). The aim of this study is to characterize hippocampus in MR images using Texture analysis features which enabling features of tissues in different clinical status in Sudanese population. This study is attempt to study the hippocampus by using MRI special protocol (T2 coronal 3mm slice thickness) and computerized textural analysis. The study had been conducted in Royal Care International Hospital in a period from February 2015 to December 2017 the sample include both gender 146 (50.3%were male) and 144 (49.7%were female) their ages between1-90 years old, and all patients are examined in MRI department by Fillip MRI machine 1.5 tesla using head coil and brain protocol mainly coronal T2 with patients supine position. The main result reveals that the hippocampus volume for normal was bigger than the volume of abnormal patients for both Left and right side of hippocampus by relation significance .026&.024 respectively. Normal right 2.207cm, normal left is 2.071 cm .for the abnormal right 2.134 cm abnormal left 2.000 cm. No significant gender was recorded in the hippocampus volume. Significant atrophy in the hippocampus volume with increasing age were detected in main diseases. Main disease effect of hippocampus volume is Epilepsy. And the correlate between patient’s age with different pathologies shows that the patients between 51-75 years with higher number of pathology atrophy, infract and tumors. The age group 51-75 was represented highest percentage (37.7%) VI The results of texture analysis give classification accuracy of hippocampus to normal 77.8%, tumor 91.8%, infection 99.7%, while the epilepsy tissue showed a classification accuracy 81.4%. The overall classification accuracy of temporal bone area 83.1%. The study conclude that normal right hippocampus value is more than the left one, and there is no significant differences between males an and Females’ volume measurements for hippocampus to normal and abnormal patients the volume for normal was bigger than the volume of abnormal patients for both left and right side of hippocampus. The study recommend that further studies in the hippocampus textural analysis should be carried out and EEG for all patients as references and Hippocampus volume should be measure by using software method to improve the accuracy should be recommended.