Characterization of Corpus Callosum in Sudanese Population using Magnetic Resonance Imaging

Abstract

Corpus callosum is vital part of the human brain because it enhances and maintains communication between brain hemispheres. Also corpus callosum dimensions and texture might be change in respect to age which generally might insinuate or simulate pathology. The aim of this work was to provide a Sudanese index (dimension) for corpus callosum and the associated parts in the normal people and the changes in the measurement that attributed to gender and compare it with the published data. This study was conducted on 50 patients (25 male and 25 female) with normal corpus callosum, their age ranged between 10-74 years. MRI studies were performed on 1.5 Tesla (Toshiba and SIMEIENS) whole body MR systems using standard imaging head coil. The study revealed that the mean CC, genu and splenium widths 7.68, 3.60 and 5.42 cm respectively. The corpus callosum length, fronto-occipital length, fronto-corpus callosum length, and occipito-corpus callosum length were. A significant negative correlation was observed between Genu Width and Age for (r= - 0.7277) and between Trunk Width and Age for (r= - 0.3951), A negative correlation also observed between Splenium Width and Age for (r= - 0.0008). Furthermore, A significant Positive correlation was observed between Corpus Callosum Length and Age for (r= 0.082), Corpus Callosum increases in all its parts starting from 10 years until 50years then start to decrease. The study concluded that according to the normal cells adaptation the age have direct effect on the corpus callosum size and noted that increase in age lead to decrease in corpus callosum dimensions