Study on the Effects of Ketamine with some Premedications in Dogs

Abstract

Two Intramuscular anesthetics protocols based on ketamine (I.m) as anesthetic ¸ xylazine (I.m) With either diazepam (I.v) or atropine sulphate (I.v) .for this purpose two groups of dog each group consist of fivesounds male dogs (each dog acted as its own control) . The first anesthetic protocol was achieved by using ketamine (10mg kg-1) ¸ xylazine (1mgkg-1) and diazepam (0.25mg kg-1) ¸ The second protocol was conducting using ketamine (10mg kg-1) ¸ xylazine (1mgkg-1) and atropine sulphate ( 0.03mg kg-1) . Clinical parameter viz : respiratory rate ¸ heart rate and body temperature were monitored ¸ some anesthesia phases ( anesthetic phase ¸ lateral recumbency ¸ sternal recumbency ¸ recovery and total recovery time ) were recorded ¸ selected anesthetic reflex( Tongue and Jaw Relaxation, Palpebral ,Pedal and Anal Reflexes )were observed. Respiratory rate showed significant increase at 5¸ 15¸ 25 and 35 minute following administration of anesthesia with ketamine (10mg kg-1) ¸ xylazine (1mgkg-1) and diazepam (0.25mg kg-1) compared with anesthesia using ketamine (10mg kg-1) ¸ xylazine (1mgkg-1) and atropine sulphate ( 0.03mg kg-1) in dogs ¸ heart rates were significantly higher at 5¸15 and 25 minute after anesthesia compare with other anesthetic protocol .anesthesia phase such as anesthetic ¸ lateral recumbency and total recovery showed no significance difference in both anesthetic protocols ¸ however, sternal recumbency phase and recovery time showed significant differences ;It found that the duration of sternal recumbency and recovery (min) were longer in xylazine ¸ diazepam premeditated dog compared with xylazine ¸ atropine premeditated one . It could be concluded that anesthesia obtained using ketamine with premedication such as xylazine with either diazepam or atropine sulphate was safe and suitable for many surgical interventions in dogs. Key words : Ketamine ¸Xylazine ¸Diazepam ¸ Atropine ¸ Dogs.