Preparation of some mefenamic acid derivatives

Ebrahem, Fatima Mohammednour Mohammedalameen; Supervisor, Ahmed Elsadig Mohammed Saeed

dc.contributor.author	Ebrahem, Fatima Mohammednour Mohammedalameen
dc.contributor.author	Supervisor, Ahmed Elsadig Mohammed Saeed
dc.date.accessioned	2016-10-23T10:35:18Z
dc.date.available	2016-10-23T10:35:18Z
dc.date.issued	2016-07-10
dc.identifier.citation	Ebrahem, Fatima Mohammednour Mohammedalameen . Preparation of some mefenamic acid derivatives / Fatima Mohammednour Mohammedalameen Ebrahem ; Ahmed Elsadig Mohammed Saeed .- Khartoum: Sudan University of Science and Technology, college of Science, 2016 .- 68p. :ill. ;28cm .-M.Sc.	en_US
dc.identifier.uri	http://repository.sustech.edu/handle/123456789/14340
dc.description	Thesis	en_US
dc.description.abstract	Nine new substituted mefenamic acid derivatives were synthesized by the reaction between the amino group in mefenamic acid and acyl chloride to give tertiary amine and reaction of free carboxylic acid of mefenamic acid with alcohol to give ester, ACD/Lab program method for Moleculardesign was described. The results on application of ACD/Lab program in calculation and correlation of structure properties of the some mefenamic acid derivatives reported. The synthetic design of these compounds was achieved through retrosynthetic analysis (RSA) approach. The reaction progress for all synthesized compounds was checked by (TLC) and m.p. techniques, and the structures of the synthesized compounds were confirmed using IR, 1HNMR, UV, and GC-MS.	en_US
dc.description.sponsorship	Sudan University of Science and Technology	en_US
dc.language.iso	en	en_US
dc.publisher	Sudan University of Science and Technology	en_US
dc.subject	Chemistry	en_US
dc.subject	mefenamic acid derivatives	en_US
dc.subject	Mefenamic acid	en_US
dc.title	Preparation of some mefenamic acid derivatives	en_US
dc.title.alternative	تحضیر بعض مشتقات حمض المیفینامیك	en_US
dc.type	Thesis	en_US