Estimation of Serum Lipid Profile in Sudanese Patients with Acute Myocardial Infarction

Abstract

An analytical case control study conducted during the period from January to July 2011, compared serum levels of total cholesterol, triglycerides, high density lipoproteins and low density lipoproteins of 30 acute myocardial infarction patients (as test group), 30 health subject (as control group), and 30 admitted individual with no AMI (as base control). Participants in this study were from Alshab hospital. The serum levels of triglycerides, total cholesterol, high density lipoproteins and low density lipoproteins were measured using A25 Bio System Chemistry analyzer and commercial kits from Bio System Company. The mean of the serum levels of triglycerides of the test group was significantly increased when compared to control group , (P= 0.003), while there was no significant difference when compared to base control , (P= 0.186). The mean of the serum levels of total cholesterol, high density lipoproteins, and low density lipoproteins of the test group showed no significant difference when compared to control group, (p=0.473), (P= 0.056), (P=0.856) and base control, (p= 0.061), (P= 0.273), (P= 0.177). In the AMI (test group) the serum levels of triglyceride showed no correlation with age P.value< 0.05Whereas the serum levels of total cholesterol and low density lipoproteins showed a weak positive correlation P.value < 0.05. The serum levels of high density lipoproteins showed no correlation with age P.value< 0.05 . From the results of this study, it is concluded that there are no difference in serum levels of total cholesterol, low density lipoproteins and high density lipoproteins and significant increase in triglyceride.