Determination of Serum Levels of Triglyceride & High Density Lipoproteins among Sudanese with Type 2 Diabetes Mellitus Attending Advance Diagnostic Center in Khartoum State in reference to BMI and gender 2013-2014

Abstract

A case control study conducted during the period from December 2013 to March 2014 to determine serum levels of triglyceride and high density lipoprotein cholesterol among Sudanese with diabetes mellitus type 2 in reference to BMI and gender of 70 Sudanese individual, 50 of them with type 2 diabetes mellitus (25 males and 25 females) as a test group and 20 apparently healthy individual ( 10 males and 10 females) as control group. Participants in this study were from Advance Diagnostic Center in Khartoum state, Sudan. Males and females were matched in term of age , sex and BMI. The serum levels of triglycerides and high density lipoprotein cholesterol were measured using autoanalyzer and commercial kits from Mindray company .The results of this study was analyzed by (SPSS 11.5). The mean of serum levels of triglycerides and high density lipoprotein cholesterol were not significantly differ when compared with control group (p= o.170 , p= 0.523) respectively. The mean of the serum levels of triglycerides was not significantly differ when diabetic males compared to diabetic females (p= 0.728). The mean of serum levels of high 4‫‪diabetic‬‬ ‫‪females‬‬ ‫‪compared‬‬ ‫‪to‬‬ ‫‪diabetic‬‬ ‫‪males‬‬ ‫=‪(p‬‬ ‫‪0.018).‬‬ ‫‪In‬‬ ‫‪the‬‬ ‫‪diabetic‬‬ ‫‪group,‬‬ ‫‪the‬‬ ‫‪serum‬‬ ‫‪levels‬‬ ‫‪of‬‬ ‫‪triglycerides‬‬ ‫‪showed‬‬ ‫‪a‬‬ ‫‪weak‬‬ ‫‪significant‬‬ ‫‪positive‬‬ ‫‪correlation‬‬ ‫‪with‬‬ ‫‪duration‬‬ ‫‪and‬‬ ‫‪insignifiacant‬‬ ‫‪positive‬‬ ‫‪correlation‬‬ ‫‪with‬‬ ‫‪BMI.‬‬ ‫‪In‬‬ ‫‪the‬‬ ‫‪diabetic‬‬ ‫‪group,‬‬ ‫‪the‬‬ ‫‪serum‬‬ ‫‪levels‬‬ ‫‪of‬‬ ‫‪high‬‬ ‫‪density‬‬ ‫‪lipoprotein‬‬ ‫‪cholesterol‬‬ ‫‪showed‬‬ ‫‪a‬‬ ‫‪weak‬‬ ‫‪insignificant‬‬ ‫‪negative‬‬ ‫‪correlation‬‬ ‫‪with‬‬ ‫‪duration‬‬ ‫‪and‬‬ ‫‪BMI.‬‬ ‫‪From‬‬ ‫‪the‬‬ ‫‪results‬‬ ‫‪of‬‬ ‫‪this‬‬ ‫‪study,‬‬ ‫‪it‬‬ ‫‪is‬‬ ‫‪concluded‬‬ ‫‪that:‬‬ ‫‪diabetes‬‬ ‫‪mellitus‬‬ ‫‪increase‬‬ ‫‪risk‬‬ ‫‪of‬‬ ‫‪cardiovascular‬‬ ‫‪diseases‬‬ ‫‪in‬‬ ‫‪females‬‬ ‫‪more‬‬ ‫‪than‬‬ ‫‪males‬‬ ‫‪.‬‬