Plasma Levels of Calcium, Phosphate, Urea and Creatinine in Sudanese Patients with Chronic Renal Failure

Abstract

A cross-sectional study conducted during the period October 2008 to February 2009 ,in IBN SINA hospital, Khartoum, compared plasma levels of calcium, phosphate, urea and creatinine of 50 patients with chronic renal failure (as a test group) and 30 apparently healthy volunteers (as a control group). The test group and the control group were matched in term of age, asocioecnomic status and sex. The plasma levels of calcium, phosphate, urea and creatinine were measured using Hitashi 902 Analyzer. Plasma phosphate, creatinine and urea were significantly raised, whereas plasma calcium was significantly reduced in the test group compared to the control group. of the patients with chronic renal failure versus controls; ( ) versus () mg/dl, p= 0.000 for plasma phosphate. () versus () mg/dl, p= 0.000 for plasma creatinine. () versus () mg/dl, p= 0.000 for plasma urea. () versus () mg/dl, p= 0.000 for plasma calcium. In the test group, plasma calcium, phosphate, urea and creatinine were not correlated with the duration of the disease. Plasma phosphate was positively correlated with the plasma creatinine, whereas the plasma calcium was negatively correlated. 4 In this study the main causes of chronic renal failure were: diabetes mellitus, hypertension, gout, renal stone, and chronic urinary tract infection.