Serodetection of Hepatitis B Virus among Nurses at El-obied city Hospital North Kordofan State

Abstract

Hepatitis B infection is one of the world's major infectious diseases and nurses have a high risk of occupational exposure to Hepatitis B Virus. This descriptive cross sectional study aimed to determine sero-prevalence of Hepatitis B virus and to determine the possible association between Hepatitis B virus and some risk factor among Nurses workersat El-obied city Hospitals North Korfofan Stateduring a period from May to October 2022. Structured questionnaire was used to collect both demographic and clinical data,Venus blood (3 ml) was taken from each participantby standard procedure,were put in plain containers to clot then centrifuged at 5000 rpm for5 minutes and serum was obtained and kept at -20ͦ C until used . The serum sample were examined by Enzyme Linked ImmunosorbentAssay (ELISA) to detect HBsAg. A total of (n=78) nurses in EL-obeid city were included in this study, in which 7 (9%) were males and 71 (91%) were females, mostly were at age between 20-30 years (63%). Among Nurses there were 4 (5.1%) positive for HBs Ag and other were negative(95%). Among these There were3/4 (75%) females were positive. for HBs Ag and 1/4 (25%) males waspositive. According to age groups, there was 2(50%) of the positive result between 20-30 years ,1 (25%) in age range from 30 to 39 years and 1(25%) in age more than50 years were positive for HBs Ag. There was 2 (2/4 (50%))of positive HBsAg nurses had accidental needle stick and the othersdidn't expose to any of the possible risk factors were HBs Ag positive . The study indicated insignificant association between Hepatitis B infection and effective factor ( P> 0.05),gender ,age , accidental injury ,blood transfusion , surgicaloperation ,renal dialysis , (P.value: 0.25 , 0.75 , 0.71,0.50 , 0.98 , 0.74 , ,respectively ). This study concluded the frequencyof hepatitis B virus among the nurses are normal.